The AIDA v4 model does not explicitly cater for pump usage. Nevertheless some users have described being able to gain useful information from the downloadable AIDA program (and AIDA on-line) by setting appropriate basal levels of insulin admistration for the simulator - and then adding in extra boluses. Some of these suggestions are reproduced here, in the hope of possibly helping more people make some use of the freeware software.
In the overview that follows some familiarity with the downloadable AIDA software and / or 'AIDA on-line' is necessarily assumed.
To set up a near 'basal' level of insulin administration - it is possible to make two entries within AIDA using a long-acting insulin preparation (e.g. Ultratard, Humulin-U, or Ultralente). These two 'injections' need to be set 12 hours apart (say in the morning and evening).
As AIDA v4 is currently limited to 4 insulin administrations (injections) per day - if you can make one of these long-acting entry times correspond to a meal (and therefore a bolus), that will permit 3 boluses to be given to AIDA.
For example, if you would like to simulate a basal regimen with 10.0 units per day, with AIDA you could enter 4 units of Ultratard in the morning (at 7am) and 6 units in the evening (at 7pm). This gives a background insulin profile that is slightly elevated in the morning - which might be fairly typical for an example patient who does not have too much of a blood glucose rise in the morning.
If you would like to simulate a bigger morning blood glucose rise (e.g. as in the 'dawn phenomenon') then with AIDA you can use a slightly more lopsided ratio. For instance, for the 10 units per day Ultratard example given above you could split the dose 3 units in the morning and 7 units in the evening, for the basal background. However one word of caution - do not split the basal dose, say 1 unit am - and 9 units pm, since the simulator will need some morning long-acting insulin to help flatten out the basal curve in the afternoon.
For the bolus doses AIDA will allow you to give the simulator up to 4 boluses (injections) of short-acting (regular) insulin - although one limitation is that 2 of these will need to be at the same times as the basal doses... Nevertheless, by giving the simulator a basal and bolus dose together (for instance in the morning), this will still leave you with at least 2 more (and possibly 3) boluses to 'play with' later in the day.
It is hoped that in this way - by experimenting with different basal and bolus regimens - users might be able to learn a bit more about balancing insulin and diet in diabetes, even with an insulin pump.
Click here to run an example simulation at AIDA on-line using this approach - with Ultratard (a long-acting preparation) being used to provide an approximate 'basal' background insulin level.
Please note, as made clear on the caveats page - such interaction with AIDA / 'AIDA on-line' is only intended for educational / self-learning / teaching or demonstration purposes. The simulator is not accurate enough to be used for individual patient blood glucose prediction or therapy planning. If you do not understand the purpose of AIDA - and / or do not appreciate its limitations - please make sure you read the caveats and disclaimer before proceeding with using the program.
Also please be aware - your mileage may vary (YMMV) - so what is useful for education for one person may not necessarily help someone else. Nevertheless some people have reported finding it helpful to apply AIDA in this way - for self-learning - so these ideas are reproduced here, in the hope / expectation that they might be of use to others.
Finally, some other vaguely technical things that you need to be aware of are:
(1) AIDA does not cater for insulin doses of less than 1 unit. Therefore only integer doses can be administered.
Clearly this simplified basal / bolus approach can only work for the more basic pump regimens. We are currently working on a dedicated version of AIDA which will permit the simulation of more sophisticated pump protocols and facilities. If you would like to be informed by email as soon as this pump version of AIDA becomes available for freeware download from this Website - please enter your email id below and press the Submit button
(2) With AIDA, the plasma insulin profile is rescaled to fit on the lower graph. Therefore you will always see some undulation to the insulin curve - and will not get a totally flat basal profile. However if you check the simulated values using the clock or fluxes functions (in the downloadable PC program) you should see that the variations are actually quite small, but magnified on the graph because of the auto-scaling.
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AIDA is a freeware diabetes software simulator program of glucose-insulin action + insulin dose & diet adjustment in diabetes mellitus. It is intended purely for education, self-learning and / or teaching use. It is not meant for individual blood glucose prediction or therapy planning. Caveats